Company Summary

FL87, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

FL87 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

The Role

We are searching for a motivated Associate Scientist/Scientist to execute in vivo studies for platform development and therapeutic proof-of-principle. More broadly, we are looking for an individual who enjoys working with animal models and brings scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment, working as part of a highly collaborative and rapidly growing team.

Key Responsibilities

• Execution and analysis of animal experiments to assess in vivo efficacy, safety, and PK/PD profiles of novel nucleic acid therapeutics
• Provide scientific and technical perspectives to advance platform development
• Develop in-house capabilities to support work performed at CROs
• Effectively communicate experimental findings in oral, written, and visual formats
• Work independently and collaboratively in a multidisciplinary team environment

Qualifications

• B.S., M.S., or Ph.D in relevant discipline with 8+ years (B.S.), or 6+ years (M.S.), or 1+ years (Ph.D) of experience (level adjusted according to experience)
• Deep experience executing in vivo studies, ideally involving gene delivery and/or nucleic acid based therapeutics in rat or mouse
• Experience with dosing of therapeutics via intravenous, intraperitoneal, subcutaneous routes of administration
• Experience collecting material (blood, tissue, etc) for ex vivo analysis and processing with ex vivo analytical assays such as ELISA, FACS, MSD, qPCR, etc. is a plus
• Experience with histological tissue analysis (IHC/IF, ISH, H&E, etc.) is a plus
• Experience with various mouse and rat models of diseases is a plus
• Strong communication and interpersonal skills
• Strong organizational, analytical, and problem-solving skills
• Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment

More About Flagship Pioneering

We are creative optimists and we would love for you to consider joining our team!  See all our open opportunities across Flagship Pioneering’s Ecosystem!

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.  Learn more about our Company Creation Model. Can Breakthrough Innovations Be Made Systematically? A Conversation With Noubar Afeyan, Flagship Pioneering’s CEO.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.