Company Overview: Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through chemistry. We are pioneering the development of SynteinsTM, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional chemists who are passionate about driving chemical innovation in biotechnology.
Abiologics was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents.
Position Summary: Abiologics is seeking a visionary and strategic leader to join our executive team as the Vice President, Head of Medicinal Chemistry. In this influential role, you will spearhead our efforts to revolutionize macromolecular medicine through innovative chemistry. You will lead and mentor a high-performing team of scientists, driving the development and execution of cutting-edge synthesis technologies and strategies to discover and optimize Synteins™ as therapeutic medicines. Your leadership will be pivotal in advancing our platform, integrating multidisciplinary insights, and shaping the future of medicines.
Responsibilities:
- Lead the peptide medicinal chemistry strategy, aligning with Abiologics' mission to advance SynteinsTM from discovery to development candidate.
- Cultivate a high-performing team of chemists and manage external collaborations with CROs to accelerate R&D objectives.
- Foster cross-functional collaboration with biology and computational teams to integrate computational techniques and biological insights into medicinal chemistry efforts.
- Innovate and optimize synthetic peptide-based drug candidates using medicinal chemistry strategies, leveraging non-canonical amino acids and novel synthetic approaches.
- Oversee resourcing and budgeting for the chemistry group, ensuring alignment with strategic goals.
Qualifications:
- Ph.D. in Peptide/Organic/Medicinal Chemistry with 10+ years of industry experience and a strong track record in drug discovery, including peptide modalities.
- Proven experience in leading drug discovery programs from discovery to optimization and development candidate, particularly with peptide-based therapeutics.
- Expertise in medicinal chemistry approaches, including the use of non-canonical amino acids to enhance compound efficacy and drug-like properties.
- Strong leadership and management skills with experience guiding diverse teams and building collaborative partnerships with external organizations.
- Demonstrated ability and passion for people leadership and talent development
- A desire to be part of a highly innovative company and be hands-on as needed in the lab to drive trailblazing research Excellent communication skills and proven ability to work collaboratively in a cross-functional, fast-paced, and innovative environment.
- Excellent communication skills and proven ability to work collaboratively in a cross-functional, fast-paced, and innovative environment.
- Preferred: Experience with utilizing computational chemistry tools and structure-based drug design principles for lead identification and optimization
More About Flagship Pioneering
Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.